Targeted delivery of proteins across the blood–brain barrier
نویسندگان
چکیده
منابع مشابه
Ultrasound-targeted nanoparticle delivery across the blood-brain barrier
Background/introduction The delivery of systemically administered drugs and genes to the CNS is hindered by both the blood-brain barrier (BBB), which limits transport from the bloodstream to the brain to only a few privileged molecules, and the nanoporous electrostatically charged tissue space, denoted here as the “brain tissue barrier” (BTB). Our group engineers targeted drug and gene delivery...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2007
ISSN: 0027-8424
DOI: 10.1073/pnas.0702170104